nutrient

Valine

A branched-chain essential amino acid with a glucogenic carbon route.

Educational draft · Human scientific and editorial review pending. About review status

Valine is incorporated into proteins and its carbon portion can enter metabolism as succinyl-CoA after breakdown.

How it works

A glucogenic carbon route

Glucogenic means that valine’s carbon portion can form intermediates used in pathways that make glucose; it does not describe an immediate change in blood glucose.

Related topics

Worth knowing

  • It is required from dietary protein. Humans cannot synthesise enough valine and obtain it from dietary protein.

A closer look

Its route differs from other branched-chain amino acids

Leucine, isoleucine and valine share a branched structure but have different carbon-skeleton fates.

Its side chain is hydrophobic

Valine’s branched hydrocarbon side chain commonly contributes to the less polar interior of a folded protein.

References

Source-checked local draft.
Human editorial review pending.

  1. NIH National Library of Medicine (opens in new tab)Biochemistry, Essential Amino AcidsChecked 2026-09-05
  2. NIH National Library of Medicine (opens in new tab)Biochemistry, Protein CatabolismChecked 2026-09-05
  3. NIH National Library of Medicine (opens in new tab)Biochemistry, Primary Protein StructureChecked 2026-09-05

Take it into the kitchen

Explore this nutrient in simple meals. Recipe pages show estimated amounts and missing data.

Chicken corn tortilla fold · 20 min →

Pineapple cashew chicken pan · 25 min →

Coconut ginger chicken rice · 25 min →

Compare meals by valine →