nutrient

Alanine

An amino acid that links nitrogen handling with pyruvate metabolism.

Educational draft · Human scientific and editorial review pending. About review status

Alanine can carry amino nitrogen between tissues while its carbon portion enters central energy pathways.

How it works

A nitrogen and carbon carrier

Alanine can be made from pyruvate by transamination, a reversible reaction that swaps an amino group between molecules. Removing the amino group returns its carbon portion to pyruvate.

Related topics

Worth knowing

  • It can form pyruvate. After nitrogen is removed, alanine can form pyruvate, a starting material for making glucose.

  • Synthesis makes it non-essential. Human cells can make alanine from pyruvate by transamination.

A closer look

The reaction runs both ways

Tissues can convert pyruvate to alanine when nitrogen needs carrying, or alanine back to pyruvate when carbon is needed.

Transamination is reversible

The direction of alanine and pyruvate exchange depends on tissue, nitrogen availability and metabolic state.

References

Source-checked local draft.
Human editorial review pending.

  1. NIH National Library of Medicine (opens in new tab)Biochemistry, Essential Amino AcidsChecked 2026-09-05
  2. NIH National Library of Medicine (opens in new tab)Biochemistry, Protein CatabolismChecked 2026-09-05

Take it into the kitchen

Explore this nutrient in simple meals. Recipe pages show estimated amounts and missing data.

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