nutrient
Pyridoxal 5′-phosphate
A phosphorylated, coenzyme form of vitamin B6 used by many enzymes.
Educational draft · Human scientific and editorial review pending. About review status
Pyridoxal phosphate is made and regulated in tissues; foods and products may provide different B6 vitamers.
How it works
What the form means
Pyridoxal 5′-phosphate supports amino-acid, neurotransmitter and haem metabolism as an enzyme cofactor.
Forms
Pyridoxal 5′-phosphate is a form of Vitamin B6.
Pyridoxal 5′-phosphate is a named chemical form within its parent vitamin family.
Evidence: Established · Source checked 2026-09-05 · Sources: NIH Office of Dietary Supplements: Vitamin B6: Fact Sheet for Health Professionals
Worth knowing
A working B6 coenzyme. Pyridoxal 5′-phosphate, or PLP, is an active vitamin B6 coenzyme used by enzymes involved in amino-acid metabolism and neurotransmitter and haem production.
A closer look
Why blood tests measure PLP
Plasma PLP is the most common measure of vitamin B6 status, even though the diet can provide several B6 vitamers. A PLP result therefore describes body status at the time of testing; it does not identify which food or supplement form supplied the vitamin.
References
Source-checked local draft.
Human editorial review pending.