nutrient

Glutamine

A nitrogen-carrying amino acid that the body can usually make.

Educational draft · Human scientific and editorial review pending. About review status

Glutamine is made from glutamate and ammonia and donates nitrogen to biosynthetic reactions. Its use can change with tissue demand and physiological state.

How it works

Nitrogen donor and metabolic shuttle

Glutamine carries nitrogen between tissues and can serve as a renal fuel. Its carbon portion can also re-enter central metabolism.

Related topics

Worth knowing

  • It is part of the free amino-acid pool. Glutamine is released when proteins are broken down and can be reused for new synthesis or other reactions.

A closer look

Different tissues use it differently

The kidney can use glutamine as a fuel. Its use as an energy source or nitrogen carrier depends on the tissue and metabolic state.

References

Source-checked local draft.
Human editorial review pending.

  1. NIH National Library of Medicine (opens in new tab)Biochemistry, Essential Amino AcidsChecked 2026-09-05
  2. NIH National Library of Medicine (opens in new tab)Biochemistry, Protein CatabolismChecked 2026-09-05