body system
Bone
Bone tissue is continuously built and remodeled.
About Bone
Vitamin D supports normal bone mineralization by helping maintain calcium and phosphate availability. This is a physiological role, not a promise that supplementation prevents fractures for everyone.
Where does vitamin D come from—and where does it go?Related topics
Vitamin D supports mineralisation in Bone
Vitamin D helps maintain the calcium and phosphate concentrations needed for normal bone mineralization and remodeling.
Magnesium supports function of Bone
Magnesium contributes to bone structure and to processes involved in bone metabolism.
Manganese supports formation of Bone
Manganese-dependent enzymes participate in bone and connective-tissue formation.
Vitamin K supports protein activation in Bone
Vitamin K activates proteins involved in bone metabolism through gamma-carboxylation.
Calcium forms mineral in Bone
Calcium phosphate mineral provides much of the structural material in bone.
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Phosphorus forms mineral with calcium in Bone
Phosphate combines with calcium in the mineral phase of bone and teeth.
Fluoride is incorporated into mineralised tissue in Bone
Fluoride can be incorporated into mineralised tissue and helps tooth enamel resist acid dissolution.
References
Source-checked local draft.
Human editorial review pending.
- NIH Office of Dietary SupplementsVitamin D: Fact Sheet for Health ProfessionalsChecked 2026-09-05
- European Food Safety AuthorityVitamin D: EFSA sets dietary reference valuesChecked 2026-09-04
- NIH Office of Dietary SupplementsMagnesium: Fact Sheet for Health ProfessionalsChecked 2026-09-04
- NIH Office of Dietary SupplementsManganese: Fact Sheet for Health ProfessionalsChecked 2026-09-05
- NIH Office of Dietary SupplementsVitamin K: Fact Sheet for Health ProfessionalsChecked 2026-09-05
- NIH Office of Dietary SupplementsCalcium: Fact Sheet for Health ProfessionalsChecked 2026-09-04
- NIH Office of Dietary SupplementsPhosphorus: Fact Sheet for Health ProfessionalsChecked 2026-09-05
- NIH Office of Dietary SupplementsFluoride: Fact Sheet for Health ProfessionalsChecked 2026-09-05